b(0,+)-type amino acid transporter 1 (SLC7A9)
Homo sapiens — UniProt P82251
Data last refreshed: (UniProt release unknown)
Key facts
b(0,+)-type amino acid transporter 1 (SLC7A9) is a protein from Homo sapiens identified by UniProt accession P82251, 487 residues long. MolForge cross-references it against 0 known binders and 227 disease associations.
- UniProt accession: P82251; gene symbol SLC7A9.
- Organism: Homo sapiens.
- Length: 487 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): cystinuria, creatinine measurement and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | b(0,+)-type amino acid transporter 1 |
|---|---|
| UniProt accession | P82251 |
| Gene | SLC7A9 |
| Organism | Homo sapiens |
| Length | 487 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (227)
Diseases linked to this target (Open Targets).
- cystinuria · score 0.85
- creatinine measurement · score 0.67
- urate measurement · score 0.50
- cystine urolithiasis · score 0.50
- cystatin C measurement · score 0.49
- genetic disorder · score 0.40
- glomerular filtration rate · score 0.40
- urinary metabolite measurement · score 0.39
- cystinuria type B · score 0.37
- lysine measurement · score 0.36
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P82251-F1 | alphafold | PREDICTED | 85.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P82251.
Amino-acid sequence (487 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC7A9?
The strongest Open Targets associations for SLC7A9 are cystinuria, creatinine measurement, urate measurement, cystine urolithiasis and cystatin C measurement.
How long is the SLC7A9 protein?
The Homo sapiens SLC7A9 protein (UniProt P82251) is 487 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P82251 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P82251 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.