Large neutral amino acids transporter small subunit 1 (SLC7A5)
Homo sapiens — UniProt Q01650
Data last refreshed: (UniProt release unknown)
Key facts
Large neutral amino acids transporter small subunit 1 (SLC7A5) is a protein from Homo sapiens identified by UniProt accession Q01650, 507 residues long. MolForge cross-references it against 8 known binders and 365 disease associations.
- UniProt accession: Q01650; gene symbol SLC7A5.
- Organism: Homo sapiens.
- Length: 507 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): mean corpuscular volume, platelet count and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large neutral amino acids transporter small subunit 1 |
|---|---|
| UniProt accession | Q01650 |
| Gene | SLC7A5 |
| Organism | Homo sapiens |
| Length | 507 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (365)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.51
- platelet count · score 0.49
- mean corpuscular hemoglobin · score 0.49
- mean corpuscular hemoglobin concentration · score 0.48
- hemoglobin measurement · score 0.47
- hematocrit · score 0.45
- platelet crit · score 0.41
- mean reticulocyte volume · score 0.41
- protein measurement · score 0.33
- Red cell distribution width · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q01650-F1 | alphafold | PREDICTED | 85.90 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q01650.
Amino-acid sequence (507 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC7A5?
The strongest Open Targets associations for SLC7A5 are mean corpuscular volume, platelet count, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and hemoglobin measurement.
How long is the SLC7A5 protein?
The Homo sapiens SLC7A5 protein (UniProt Q01650) is 507 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q01650 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q01650 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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