Transcription factor Sp2 (SP2)
Homo sapiens — UniProt Q02086
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor Sp2 (SP2) is a protein from Homo sapiens identified by UniProt accession Q02086, 613 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q02086; gene symbol SP2.
- Organism: Homo sapiens.
- Length: 613 amino acids.
- Top disease associations (Open Targets): hair color, birth weight and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor Sp2 |
|---|---|
| UniProt accession | Q02086 |
| Gene | SP2 |
| Organism | Homo sapiens |
| Length | 613 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- hair color · score 0.20
- birth weight · score 0.19
- mean corpuscular volume · score 0.07
- hair colour measurement · score 0.05
- autoimmune disease · score 0.03
- platelet crit · score 0.03
- erythrocyte count · score 0.03
- fat body mass · score 0.02
- FEV/FVC ratio · score 0.02
- lean body mass · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q02086-F1 | alphafold | PREDICTED | 44.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q02086.
Amino-acid sequence (613 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SP2?
The strongest Open Targets associations for SP2 are hair color, birth weight, mean corpuscular volume, hair colour measurement and autoimmune disease.
How long is the SP2 protein?
The Homo sapiens SP2 protein (UniProt Q02086) is 613 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q02086 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q02086 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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