Sperm-associated antigen 11B (SPAG11B)
Homo sapiens — UniProt Q08648
Data last refreshed: (UniProt release unknown)
Key facts
Sperm-associated antigen 11B (SPAG11B) is a protein from Homo sapiens identified by UniProt accession Q08648, 103 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q08648; gene symbol SPAG11B.
- Organism: Homo sapiens.
- Length: 103 amino acids.
- Top disease associations (Open Targets): non-small cell lung carcinoma, varicocele and acute myeloid leukemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sperm-associated antigen 11B |
|---|---|
| UniProt accession | Q08648 |
| Gene | SPAG11B |
| Organism | Homo sapiens |
| Length | 103 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- non-small cell lung carcinoma · score 0.03
- varicocele · score 0.02
- acute myeloid leukemia · score 0.01
- lung adenocarcinoma · score 0.01
- infect · score 0.00
- infection · score 0.00
- Infertility · score 0.00
- male infertility · score 0.00
- Epididymitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q08648-F1 | alphafold | PREDICTED | 64.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q08648.
Amino-acid sequence (103 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPAG11B?
The strongest Open Targets associations for SPAG11B are non-small cell lung carcinoma, varicocele, acute myeloid leukemia, lung adenocarcinoma and infect.
How long is the SPAG11B protein?
The Homo sapiens SPAG11B protein (UniProt Q08648) is 103 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q08648 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q08648 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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