Schlafen family member 5 (SLFN5)
Homo sapiens — UniProt Q08AF3
Data last refreshed: (UniProt release unknown)
Key facts
Schlafen family member 5 (SLFN5) is a protein from Homo sapiens identified by UniProt accession Q08AF3, 891 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q08AF3; gene symbol SLFN5.
- Organism: Homo sapiens.
- Length: 891 amino acids.
- Top disease associations (Open Targets): triglyceride measurement, sphingomyelin measurement and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Schlafen family member 5 |
|---|---|
| UniProt accession | Q08AF3 |
| Gene | SLFN5 |
| Organism | Homo sapiens |
| Length | 891 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.30
- sphingomyelin measurement · score 0.15
- blood protein measurement · score 0.05
- ulcerative colitis · score 0.02
- lung carcinoma · score 0.02
- juvenile dermatomyositis · score 0.01
- Sepsis · score 0.01
- cystic fibrosis · score 0.01
- acute quadriplegic myopathy · score 0.01
- pancreatic ductal adenocarcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q08AF3-F1 | alphafold | PREDICTED | 87.59 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q08AF3.
Amino-acid sequence (891 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLFN5?
The strongest Open Targets associations for SLFN5 are triglyceride measurement, sphingomyelin measurement, blood protein measurement, ulcerative colitis and lung carcinoma.
How long is the SLFN5 protein?
The Homo sapiens SLFN5 protein (UniProt Q08AF3) is 891 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q08AF3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q08AF3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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