Uncharacterized protein SPEM2 (SPEM2)
Homo sapiens — UniProt Q0P670
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein SPEM2 (SPEM2) is a protein from Homo sapiens identified by UniProt accession Q0P670, 501 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q0P670; gene symbol SPEM2.
- Organism: Homo sapiens.
- Length: 501 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, systolic blood pressure and asthma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein SPEM2 |
|---|---|
| UniProt accession | Q0P670 |
| Gene | SPEM2 |
| Organism | Homo sapiens |
| Length | 501 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.21
- systolic blood pressure · score 0.10
- asthma · score 0.09
- red blood cell density measurement · score 0.05
- heel bone mineral density · score 0.04
- lean body mass · score 0.04
- neutrophil count · score 0.04
- erythrocyte count · score 0.04
- serum gamma-glutamyl transferase measurement · score 0.03
- bone quantitative ultrasound measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q0P670-F1 | alphafold | PREDICTED | 49.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q0P670.
Amino-acid sequence (501 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPEM2?
The strongest Open Targets associations for SPEM2 are sex hormone-binding globulin measurement, systolic blood pressure, asthma, red blood cell density measurement and heel bone mineral density.
How long is the SPEM2 protein?
The Homo sapiens SPEM2 protein (UniProt Q0P670) is 501 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q0P670 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q0P670 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.