Leiomodin-3 (LMOD3)
Homo sapiens — UniProt Q0VAK6
Data last refreshed: (UniProt release unknown)
Key facts
Leiomodin-3 (LMOD3) is a protein from Homo sapiens identified by UniProt accession Q0VAK6, 560 residues long. MolForge cross-references it against 0 known binders and 200 disease associations.
- UniProt accession: Q0VAK6; gene symbol LMOD3.
- Organism: Homo sapiens.
- Length: 560 amino acids.
- Top disease associations (Open Targets): nemaline myopathy, typical nemaline myopathy and severe congenital nemaline myopathy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leiomodin-3 |
|---|---|
| UniProt accession | Q0VAK6 |
| Gene | LMOD3 |
| Organism | Homo sapiens |
| Length | 560 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (200)
Diseases linked to this target (Open Targets).
- nemaline myopathy · score 0.77
- typical nemaline myopathy · score 0.37
- severe congenital nemaline myopathy · score 0.37
- genetic disorder · score 0.19
- mean corpuscular volume · score 0.17
- mean corpuscular hemoglobin · score 0.14
- mean corpuscular hemoglobin concentration · score 0.13
- celiac disease · score 0.10
- cortical surface area measurement · score 0.09
- Malabsorption · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q0VAK6-F1 | alphafold | PREDICTED | 67.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q0VAK6.
Amino-acid sequence (560 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LMOD3?
The strongest Open Targets associations for LMOD3 are nemaline myopathy, typical nemaline myopathy, severe congenital nemaline myopathy, genetic disorder and mean corpuscular volume.
How long is the LMOD3 protein?
The Homo sapiens LMOD3 protein (UniProt Q0VAK6) is 560 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q0VAK6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q0VAK6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.