Adipogenin (ADIG)
Homo sapiens — UniProt Q0VDE8
Data last refreshed: (UniProt release unknown)
Key facts
Adipogenin (ADIG) is a protein from Homo sapiens identified by UniProt accession Q0VDE8, 80 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q0VDE8; gene symbol ADIG.
- Organism: Homo sapiens.
- Length: 80 amino acids.
- Top disease associations (Open Targets): age at menarche, hereditary persistence of fetal hemoglobin-sickle cell disease syndrome and alpha-thalassemia-myelodysplastic syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Adipogenin |
|---|---|
| UniProt accession | Q0VDE8 |
| Gene | ADIG |
| Organism | Homo sapiens |
| Length | 80 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- age at menarche · score 0.06
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.05
- alpha-thalassemia-myelodysplastic syndrome · score 0.05
- hemoglobin D disease · score 0.05
- delta-beta-thalassemia · score 0.05
- CIDEC-related familial partial lipodystrophy · score 0.05
- dominant beta-thalassemia · score 0.05
- beta-thalassemia-X-linked thrombocytopenia syndrome · score 0.04
- hemoglobin E-beta-thalassemia syndrome · score 0.04
- hemoglobin C-beta-thalassemia syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q0VDE8-F1 | alphafold | PREDICTED | 68.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q0VDE8.
Amino-acid sequence (80 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ADIG?
The strongest Open Targets associations for ADIG are age at menarche, hereditary persistence of fetal hemoglobin-sickle cell disease syndrome, alpha-thalassemia-myelodysplastic syndrome, hemoglobin D disease and delta-beta-thalassemia.
How long is the ADIG protein?
The Homo sapiens ADIG protein (UniProt Q0VDE8) is 80 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q0VDE8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q0VDE8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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