Cilia- and flagella- associated protein 210 (CFAP210)

About Cilia- and flagella- associated protein 210

Cilia- and flagella- associated protein 210 (CFAP210) is a protein from Homo sapiens identified by UniProt accession Q0VFZ6, 552 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Cilia- and flagella- associated protein 210
UniProt accession	Q0VFZ6
Gene	CFAP210
Organism	Homo sapiens
Length	552 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

platelet crit · score 0.26
lymphocyte count · score 0.22
monocyte count · score 0.21
platelet count · score 0.11
appendicular lean mass · score 0.06
body height · score 0.03
systolic blood pressure · score 0.03
squamous cell carcinoma · score 0.02
ependymoma · score 0.02
Abnormal sperm morphology · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q0VFZ6-F1	alphafold	PREDICTED	80.98	—

Amino-acid sequence (552 residues)

MDTSSEMLVR FGRRCGRAKE STEIRNSEED QVLYLPLLPS KVDLQQVTII PHDEWKRIQD SLDRLTREAA CLRAERKAKK EMHLRSQEVV KHWTNTYAGM KEQKLEAKKK RDEEIEAERQ ILDLEEEIYK QGKRKKAIEN AKQYQFYQTE RVKNFHSGLL LSRVMKERDA QIEFRKSKIK SDKKWEEQLK LNIEKAFKEE QEKAEKRHRE RVALAKDHLK QIKEHEEEEE RRKKYEEKDA EEIKRQNALY EIEMRKKLEK KREEMHESRR RFLEHMQDKH IIKAVEQQQQ EEEDEKMRKF IKAKKRLIQM GKEKEAETHR LMEKRRERIH NFLSELLKEK LDNEDMIIAR DIAEAEAEWE KREREKDEKN KAELKTIAEY RAIVMKNKEE EERQRKIEAK EQLLAVMKAD QIFWEHEKEK KCKADKEHQE VQDAHIQQMA KNKFNAKQAK QAELDYCRLT EALVAEKEKE FQDYAREVIE LESETTNKYI YPLVKAVQEG PGGGRGPVFV DRGGLRPSYQ ANDVTGVQLP FYNSQGPKYN FQKSKRRLGF TW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards