Fatty acid-binding protein 9 (FABP9)
Homo sapiens — UniProt Q0Z7S8
Data last refreshed: (UniProt release unknown)
Key facts
Fatty acid-binding protein 9 (FABP9) is a protein from Homo sapiens identified by UniProt accession Q0Z7S8, 132 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.
- UniProt accession: Q0Z7S8; gene symbol FABP9.
- Organism: Homo sapiens.
- Length: 132 amino acids.
- Top disease associations (Open Targets): azoospermia, male infertility with teratozoospermia due to single gene mutation and spermatogenic failure 20.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Fatty acid-binding protein 9 |
|---|---|
| UniProt accession | Q0Z7S8 |
| Gene | FABP9 |
| Organism | Homo sapiens |
| Length | 132 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (81)
Diseases linked to this target (Open Targets).
- azoospermia · score 0.10
- male infertility with teratozoospermia due to single gene mutation · score 0.08
- spermatogenic failure 20 · score 0.07
- spermatogenic failure 51 · score 0.07
- spermatogenic failure 24 · score 0.06
- spermatogenic failure 72 · score 0.06
- partial chromosome Y deletion · score 0.06
- spermatogenic failure 18 · score 0.06
- spermatogenic failure 46 · score 0.06
- spermatogenic failure 27 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q0Z7S8-F1 | alphafold | PREDICTED | 96.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q0Z7S8.
Amino-acid sequence (132 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FABP9?
The strongest Open Targets associations for FABP9 are azoospermia, male infertility with teratozoospermia due to single gene mutation, spermatogenic failure 20, spermatogenic failure 51 and spermatogenic failure 24.
How long is the FABP9 protein?
The Homo sapiens FABP9 protein (UniProt Q0Z7S8) is 132 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q0Z7S8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q0Z7S8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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