Sorting nexin-1 (SNX1)
Homo sapiens — UniProt Q13596
Data last refreshed: (UniProt release unknown)
Key facts
Sorting nexin-1 (SNX1) is a protein from Homo sapiens identified by UniProt accession Q13596, 522 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q13596; gene symbol SNX1.
- Organism: Homo sapiens.
- Length: 522 amino acids.
- Top disease associations (Open Targets): erythrocyte count, hemoglobin measurement and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sorting nexin-1 |
|---|---|
| UniProt accession | Q13596 |
| Gene | SNX1 |
| Organism | Homo sapiens |
| Length | 522 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- erythrocyte count · score 0.18
- hemoglobin measurement · score 0.15
- mean platelet volume · score 0.11
- gonorrhea · score 0.07
- mean corpuscular volume · score 0.06
- neoplasm · score 0.04
- red blood cell density measurement · score 0.03
- hematocrit · score 0.03
- non-small cell lung carcinoma · score 0.02
- infection · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q13596-F1 | alphafold | PREDICTED | 74.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q13596.
Amino-acid sequence (522 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNX1?
The strongest Open Targets associations for SNX1 are erythrocyte count, hemoglobin measurement, mean platelet volume, gonorrhea and mean corpuscular volume.
How long is the SNX1 protein?
The Homo sapiens SNX1 protein (UniProt Q13596) is 522 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q13596 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q13596 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.