Beta-1-syntrophin (SNTB1)
Homo sapiens — UniProt Q13884
Data last refreshed: (UniProt release unknown)
Key facts
Beta-1-syntrophin (SNTB1) is a protein from Homo sapiens identified by UniProt accession Q13884, 538 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.
- UniProt accession: Q13884; gene symbol SNTB1.
- Organism: Homo sapiens.
- Length: 538 amino acids.
- Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, apolipoprotein A 1 measurement and alcohol drinking.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Beta-1-syntrophin |
|---|---|
| UniProt accession | Q13884 |
| Gene | SNTB1 |
| Organism | Homo sapiens |
| Length | 538 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.46
- apolipoprotein A 1 measurement · score 0.41
- alcohol drinking · score 0.36
- alcohol consumption measurement · score 0.36
- lip and oral cavity carcinoma · score 0.34
- type 2 diabetes mellitus · score 0.30
- pathological myopia · score 0.29
- facial morphology measurement · score 0.29
- HbA1c measurement · score 0.29
- C-reactive protein measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q13884-F1 | alphafold | PREDICTED | 77.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q13884.
Amino-acid sequence (538 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNTB1?
The strongest Open Targets associations for SNTB1 are high density lipoprotein cholesterol measurement, apolipoprotein A 1 measurement, alcohol drinking, alcohol consumption measurement and lip and oral cavity carcinoma.
How long is the SNTB1 protein?
The Homo sapiens SNTB1 protein (UniProt Q13884) is 538 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q13884 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q13884 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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