SPARC-like protein 1 (SPARCL1)
Homo sapiens — UniProt Q14515
Data last refreshed: (UniProt release unknown)
Key facts
SPARC-like protein 1 (SPARCL1) is a protein from Homo sapiens identified by UniProt accession Q14515, 664 residues long. MolForge cross-references it against 0 known binders and 185 disease associations.
- UniProt accession: Q14515; gene symbol SPARCL1.
- Organism: Homo sapiens.
- Length: 664 amino acids.
- Top disease associations (Open Targets): blood protein measurement, SPARC-like protein 1 measurement and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SPARC-like protein 1 |
|---|---|
| UniProt accession | Q14515 |
| Gene | SPARCL1 |
| Organism | Homo sapiens |
| Length | 664 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (185)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.47
- SPARC-like protein 1 measurement · score 0.34
- protein measurement · score 0.30
- neoplasm · score 0.09
- cancer · score 0.08
- gastrointestinal stromal tumor · score 0.08
- osteosarcoma · score 0.08
- esophageal squamous cell carcinoma · score 0.07
- inherited lipid metabolism disorder · score 0.07
- breast cancer · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q14515-F1 | alphafold | PREDICTED | 59.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q14515.
Amino-acid sequence (664 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPARCL1?
The strongest Open Targets associations for SPARCL1 are blood protein measurement, SPARC-like protein 1 measurement, protein measurement, neoplasm and cancer.
How long is the SPARCL1 protein?
The Homo sapiens SPARCL1 protein (UniProt Q14515) is 664 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q14515 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q14515 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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