Solute carrier family 75 member 1 (SLC75A1)
Homo sapiens — UniProt Q14728
Data last refreshed: (UniProt release unknown)
Key facts
Solute carrier family 75 member 1 (SLC75A1) is a protein from Homo sapiens identified by UniProt accession Q14728, 455 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q14728; gene symbol SLC75A1.
- Organism: Homo sapiens.
- Length: 455 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, diet measurement and smoking status measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Solute carrier family 75 member 1 |
|---|---|
| UniProt accession | Q14728 |
| Gene | SLC75A1 |
| Organism | Homo sapiens |
| Length | 455 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.06
- diet measurement · score 0.06
- smoking status measurement · score 0.06
- smoking initiation · score 0.05
- self reported educational attainment · score 0.05
- smoking behaviour measurement · score 0.05
- transient myeloproliferative syndrome · score 0.05
- BMI-adjusted hip circumference · score 0.05
- cups of coffee per day measurement · score 0.05
- pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 9 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q14728-F1 | alphafold | PREDICTED | 91.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q14728.
Amino-acid sequence (455 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC75A1?
The strongest Open Targets associations for SLC75A1 are sex hormone-binding globulin measurement, diet measurement, smoking status measurement, smoking initiation and self reported educational attainment.
How long is the SLC75A1 protein?
The Homo sapiens SLC75A1 protein (UniProt Q14728) is 455 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q14728 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q14728 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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