Sarcolemmal membrane-associated protein (SLMAP)
Homo sapiens — UniProt Q14BN4
Data last refreshed: (UniProt release unknown)
Key facts
Sarcolemmal membrane-associated protein (SLMAP) is a protein from Homo sapiens identified by UniProt accession Q14BN4, 828 residues long. MolForge cross-references it against 0 known binders and 86 disease associations.
- UniProt accession: Q14BN4; gene symbol SLMAP.
- Organism: Homo sapiens.
- Length: 828 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Brugada syndrome and neutrophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sarcolemmal membrane-associated protein |
|---|---|
| UniProt accession | Q14BN4 |
| Gene | SLMAP |
| Organism | Homo sapiens |
| Length | 828 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (86)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- Brugada syndrome · score 0.42
- neutrophil count · score 0.28
- diastolic blood pressure · score 0.27
- vital capacity · score 0.26
- FEV/FVC ratio · score 0.25
- forced expiratory volume · score 0.25
- neutrophil percentage of leukocytes · score 0.19
- infantile hypertrophic pyloric stenosis · score 0.16
- leukocyte count · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q14BN4-F1 | alphafold | PREDICTED | 77.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q14BN4.
Amino-acid sequence (828 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLMAP?
The strongest Open Targets associations for SLMAP are neurodegenerative disease, Brugada syndrome, neutrophil count, diastolic blood pressure and vital capacity.
How long is the SLMAP protein?
The Homo sapiens SLMAP protein (UniProt Q14BN4) is 828 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q14BN4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q14BN4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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