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Sorting nexin-17 (SNX17)

Homo sapiens — UniProt Q15036

Gene: SNX17Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Sorting nexin-17 (SNX17) is a protein from Homo sapiens identified by UniProt accession Q15036, 470 residues long. MolForge cross-references it against 0 known binders and 197 disease associations.

  • UniProt accession: Q15036; gene symbol SNX17.
  • Organism: Homo sapiens.
  • Length: 470 amino acids.
  • Top disease associations (Open Targets): triglyceride measurement, alcohol consumption measurement and alcohol drinking.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSorting nexin-17
UniProt accessionQ15036
GeneSNX17
OrganismHomo sapiens
Length470 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (197)

Diseases linked to this target (Open Targets).

  • triglyceride measurement · score 0.38
  • alcohol consumption measurement · score 0.25
  • alcohol drinking · score 0.24
  • low density lipoprotein cholesterol measurement · score 0.20
  • urinary albumin to creatinine ratio · score 0.19
  • retinitis pigmentosa · score 0.18
  • gout · score 0.18
  • type 2 diabetes mellitus · score 0.18
  • blood protein measurement · score 0.16
  • reticulocyte count · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q15036-F1alphafoldPREDICTED82.12—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q15036.

Amino-acid sequence (470 residues)

MHFSIPETES RSGDSGGSAY VAYNIHVNGV LHCRVRYSQL LGLHEQLRKE YGANVLPAFP PKKLFSLTPA EVEQRREQLE KYMQAVRQDP LLGSSETFNS FLRRAQQETQ QVPTEEVSLE VLLSNGQKVL VNVLTSDQTE DVLEAVAAKL DLPDDLIGYF SLFLVREKED GAFSFVRKLQ EFELPYVSVT SLRSQEYKIV LRKSYWDSAY DDDVMENRVG LNLLYAQTVS DIERGWILVT KEQHRQLKSL QEKVSKKEFL RLAQTLRHYG YLRFDACVAD FPEKDCPVVV SAGNSELSLQ LRLPGQQLRE GSFRVTRMRC WRVTSSVPLP SGSTSSPGRG RGEVRLELAF EYLMSKDRLQ WVTITSPQAI MMSICLQSMV DELMVKKSGG SIRKMLRRRV GGTLRRSDSQ QAVKSPPLLE SPDATRESMV KLSSKLSAVS LRGIGSPSTD ASASDVHGNF AFEGIGDEDL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SNX17?

The strongest Open Targets associations for SNX17 are triglyceride measurement, alcohol consumption measurement, alcohol drinking, low density lipoprotein cholesterol measurement and urinary albumin to creatinine ratio.

How long is the SNX17 protein?

The Homo sapiens SNX17 protein (UniProt Q15036) is 470 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ15036
GeneSNX17
OrganismHomo sapiens
Length470
Binders0
Diseases197
View on UniProt