U11/U12 small nuclear ribonucleoprotein 35 kDa protein (SNRNP35)
Homo sapiens — UniProt Q16560
Data last refreshed: (UniProt release unknown)
Key facts
U11/U12 small nuclear ribonucleoprotein 35 kDa protein (SNRNP35) is a protein from Homo sapiens identified by UniProt accession Q16560, 246 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q16560; gene symbol SNRNP35.
- Organism: Homo sapiens.
- Length: 246 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, urate measurement and eosinophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | U11/U12 small nuclear ribonucleoprotein 35 kDa protein |
|---|---|
| UniProt accession | Q16560 |
| Gene | SNRNP35 |
| Organism | Homo sapiens |
| Length | 246 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- urate measurement · score 0.07
- eosinophil count · score 0.02
- diastolic blood pressure · score 0.02
- sex hormone-binding globulin measurement · score 0.02
- low density lipoprotein cholesterol measurement · score 0.02
- post-traumatic stress disorder · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q16560-F1 | alphafold | PREDICTED | 76.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q16560.
Amino-acid sequence (246 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNRNP35?
The strongest Open Targets associations for SNRNP35 are neurodegenerative disease, urate measurement, eosinophil count, diastolic blood pressure and sex hormone-binding globulin measurement.
How long is the SNRNP35 protein?
The Homo sapiens SNRNP35 protein (UniProt Q16560) is 246 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q16560 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q16560 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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