IQ domain-containing protein J (IQCJ)
Homo sapiens — UniProt Q1A5X6
Data last refreshed: (UniProt release unknown)
Key facts
IQ domain-containing protein J (IQCJ) is a protein from Homo sapiens identified by UniProt accession Q1A5X6, 159 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q1A5X6; gene symbol IQCJ.
- Organism: Homo sapiens.
- Length: 159 amino acids.
- Top disease associations (Open Targets): neuroimaging measurement, brain volume measurement and brain measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | IQ domain-containing protein J |
|---|---|
| UniProt accession | Q1A5X6 |
| Gene | IQCJ |
| Organism | Homo sapiens |
| Length | 159 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- neuroimaging measurement · score 0.42
- brain volume measurement · score 0.38
- brain measurement · score 0.31
- smoking initiation · score 0.28
- metabolite measurement · score 0.25
- antisocial behaviour measurement · score 0.15
- attention deficit hyperactivity disorder · score 0.15
- substance abuse · score 0.15
- smoking status measurement · score 0.13
- Blackfan-Diamond anemia · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q1A5X6-F1 | alphafold | PREDICTED | 48.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q1A5X6.
Amino-acid sequence (159 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IQCJ?
The strongest Open Targets associations for IQCJ are neuroimaging measurement, brain volume measurement, brain measurement, smoking initiation and metabolite measurement.
How long is the IQCJ protein?
The Homo sapiens IQCJ protein (UniProt Q1A5X6) is 159 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q1A5X6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q1A5X6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.