Serine protease inhibitor Kazal-type 13 (SPINK13)
Homo sapiens — UniProt Q1W4C9
Data last refreshed: (UniProt release unknown)
Key facts
Serine protease inhibitor Kazal-type 13 (SPINK13) is a protein from Homo sapiens identified by UniProt accession Q1W4C9, 94 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q1W4C9; gene symbol SPINK13.
- Organism: Homo sapiens.
- Length: 94 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, nonpapillary renal cell carcinoma and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine protease inhibitor Kazal-type 13 |
|---|---|
| UniProt accession | Q1W4C9 |
| Gene | SPINK13 |
| Organism | Homo sapiens |
| Length | 94 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- nonpapillary renal cell carcinoma · score 0.07
- neoplasm · score 0.04
- kidney disease · score 0.04
- hepatorenocardiac degenerative fibrosis · score 0.04
- lung adenocarcinoma · score 0.04
- Holzgreve-Wagner-Rehder syndrome · score 0.04
- nephronophthisis 16 · score 0.04
- nephronophthisis · score 0.03
- Recurrent infections-myelofibrosis-nephromegaly syndrome · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q1W4C9-F1 | alphafold | PREDICTED | 86.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q1W4C9.
Amino-acid sequence (94 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPINK13?
The strongest Open Targets associations for SPINK13 are neurodegenerative disease, nonpapillary renal cell carcinoma, neoplasm, kidney disease and hepatorenocardiac degenerative fibrosis.
How long is the SPINK13 protein?
The Homo sapiens SPINK13 protein (UniProt Q1W4C9) is 94 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q1W4C9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q1W4C9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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