SKI/DACH domain-containing protein 1 (SKIDA1)
Homo sapiens — UniProt Q1XH10
Data last refreshed: (UniProt release unknown)
Key facts
SKI/DACH domain-containing protein 1 (SKIDA1) is a protein from Homo sapiens identified by UniProt accession Q1XH10, 908 residues long. MolForge cross-references it against 0 known binders and 133 disease associations.
- UniProt accession: Q1XH10; gene symbol SKIDA1.
- Organism: Homo sapiens.
- Length: 908 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, IGF-1 measurement and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SKI/DACH domain-containing protein 1 |
|---|---|
| UniProt accession | Q1XH10 |
| Gene | SKIDA1 |
| Organism | Homo sapiens |
| Length | 908 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (133)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- IGF-1 measurement · score 0.33
- systolic blood pressure · score 0.31
- diet measurement · score 0.31
- neuroimaging measurement · score 0.30
- cortical surface area measurement · score 0.29
- brain measurement · score 0.29
- body height · score 0.29
- insulin like growth factor measurement · score 0.26
- HbA1c measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q1XH10-F1 | alphafold | PREDICTED | 49.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q1XH10.
Amino-acid sequence (908 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SKIDA1?
The strongest Open Targets associations for SKIDA1 are neurodegenerative disease, IGF-1 measurement, systolic blood pressure, diet measurement and neuroimaging measurement.
How long is the SKIDA1 protein?
The Homo sapiens SKIDA1 protein (UniProt Q1XH10) is 908 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q1XH10 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q1XH10 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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