Ankyrin repeat domain-containing protein SOWAHA (SOWAHA)
Homo sapiens — UniProt Q2M3V2
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein SOWAHA (SOWAHA) is a protein from Homo sapiens identified by UniProt accession Q2M3V2, 549 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q2M3V2; gene symbol SOWAHA.
- Organism: Homo sapiens.
- Length: 549 amino acids.
- Top disease associations (Open Targets): creatinine measurement, IGF-1 measurement and serum gamma-glutamyl transferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein SOWAHA |
|---|---|
| UniProt accession | Q2M3V2 |
| Gene | SOWAHA |
| Organism | Homo sapiens |
| Length | 549 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- creatinine measurement · score 0.24
- IGF-1 measurement · score 0.22
- serum gamma-glutamyl transferase measurement · score 0.21
- platelet component distribution width · score 0.10
- glioblastoma multiforme · score 0.05
- atypical teratoid rhabdoid tumor · score 0.05
- medulloblastoma · score 0.04
- lean body mass · score 0.04
- Barrett's esophagus · score 0.04
- eosinophil count · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q2M3V2-F1 | alphafold | PREDICTED | 61.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q2M3V2.
Amino-acid sequence (549 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SOWAHA?
The strongest Open Targets associations for SOWAHA are creatinine measurement, IGF-1 measurement, serum gamma-glutamyl transferase measurement, platelet component distribution width and glioblastoma multiforme.
How long is the SOWAHA protein?
The Homo sapiens SOWAHA protein (UniProt Q2M3V2) is 549 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q2M3V2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q2M3V2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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