Transmembrane protein 44 (TMEM44)
Homo sapiens — UniProt Q2T9K0
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 44 (TMEM44) is a protein from Homo sapiens identified by UniProt accession Q2T9K0, 475 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q2T9K0; gene symbol TMEM44.
- Organism: Homo sapiens.
- Length: 475 amino acids.
- Top disease associations (Open Targets): electrocardiography, diastolic blood pressure and QT interval.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 44 |
|---|---|
| UniProt accession | Q2T9K0 |
| Gene | TMEM44 |
| Organism | Homo sapiens |
| Length | 475 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- electrocardiography · score 0.45
- diastolic blood pressure · score 0.29
- QT interval · score 0.28
- PHF-tau measurement · score 0.24
- hemoglobin measurement · score 0.19
- erythrocyte count · score 0.18
- hematocrit · score 0.18
- red blood cell density measurement · score 0.14
- mean corpuscular hemoglobin concentration · score 0.13
- reticulocyte count · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q2T9K0-F1 | alphafold | PREDICTED | 59.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q2T9K0.
Amino-acid sequence (475 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM44?
The strongest Open Targets associations for TMEM44 are electrocardiography, diastolic blood pressure, QT interval, PHF-tau measurement and hemoglobin measurement.
How long is the TMEM44 protein?
The Homo sapiens TMEM44 protein (UniProt Q2T9K0) is 475 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q2T9K0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q2T9K0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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