WD40 repeat-containing protein SMU1 (SMU1)
Homo sapiens — UniProt Q2TAY7
Data last refreshed: (UniProt release unknown)
Key facts
WD40 repeat-containing protein SMU1 (SMU1) is a protein from Homo sapiens identified by UniProt accession Q2TAY7, 513 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q2TAY7; gene symbol SMU1.
- Organism: Homo sapiens.
- Length: 513 amino acids.
- Top disease associations (Open Targets): age at menopause, self reported educational attainment and aspartate aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD40 repeat-containing protein SMU1 |
|---|---|
| UniProt accession | Q2TAY7 |
| Gene | SMU1 |
| Organism | Homo sapiens |
| Length | 513 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- age at menopause · score 0.07
- self reported educational attainment · score 0.05
- aspartate aminotransferase measurement · score 0.05
- erythrocyte count · score 0.05
- mathematical ability · score 0.04
- urate measurement · score 0.04
- blood protein measurement · score 0.04
- body height · score 0.03
- reticulocyte measurement · score 0.03
- hemoglobin measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q2TAY7-F1 | alphafold | PREDICTED | 82.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q2TAY7.
Amino-acid sequence (513 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMU1?
The strongest Open Targets associations for SMU1 are age at menopause, self reported educational attainment, aspartate aminotransferase measurement, erythrocyte count and mathematical ability.
How long is the SMU1 protein?
The Homo sapiens SMU1 protein (UniProt Q2TAY7) is 513 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q2TAY7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q2TAY7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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