Kelch-like protein 38 (KLHL38)
Homo sapiens — UniProt Q2WGJ6
Data last refreshed: (UniProt release unknown)
Key facts
Kelch-like protein 38 (KLHL38) is a protein from Homo sapiens identified by UniProt accession Q2WGJ6, 581 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q2WGJ6; gene symbol KLHL38.
- Organism: Homo sapiens.
- Length: 581 amino acids.
- Top disease associations (Open Targets): electrocardiography, QRS duration and carotid artery intima media thickness.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kelch-like protein 38 |
|---|---|
| UniProt accession | Q2WGJ6 |
| Gene | KLHL38 |
| Organism | Homo sapiens |
| Length | 581 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- electrocardiography · score 0.43
- QRS duration · score 0.37
- carotid artery intima media thickness · score 0.28
- atrial fibrillation · score 0.27
- heel bone mineral density · score 0.26
- breast carcinoma · score 0.26
- cortical thickness · score 0.26
- systolic blood pressure · score 0.26
- PR interval · score 0.25
- aortic measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q2WGJ6-F1 | alphafold | PREDICTED | 90.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q2WGJ6.
Amino-acid sequence (581 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KLHL38?
The strongest Open Targets associations for KLHL38 are electrocardiography, QRS duration, carotid artery intima media thickness, atrial fibrillation and heel bone mineral density.
How long is the KLHL38 protein?
The Homo sapiens KLHL38 protein (UniProt Q2WGJ6) is 581 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q2WGJ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q2WGJ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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