Beta-defensin 109B (DEFB109B)
Homo sapiens — UniProt Q30KR1
Data last refreshed: (UniProt release unknown)
Key facts
Beta-defensin 109B (DEFB109B) is a protein from Homo sapiens identified by UniProt accession Q30KR1, 87 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q30KR1; gene symbol DEFB109B.
- Organism: Homo sapiens.
- Length: 87 amino acids.
- Top disease associations (Open Targets): infection, infect and chronic obstructive pulmonary disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Beta-defensin 109B |
|---|---|
| UniProt accession | Q30KR1 |
| Gene | DEFB109B |
| Organism | Homo sapiens |
| Length | 87 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- infection · score 0.00
- infect · score 0.00
- chronic obstructive pulmonary disease · score 0.00
- osteosarcoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q30KR1-F1 | alphafold | PREDICTED | 81.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q30KR1.
Amino-acid sequence (87 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DEFB109B?
The strongest Open Targets associations for DEFB109B are infection, infect, chronic obstructive pulmonary disease and osteosarcoma.
How long is the DEFB109B protein?
The Homo sapiens DEFB109B protein (UniProt Q30KR1) is 87 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q30KR1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q30KR1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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