Sodium-dependent organic anion transporter (SLC10A6)
Homo sapiens — UniProt Q3KNW5
Data last refreshed: (UniProt release unknown)
Key facts
Sodium-dependent organic anion transporter (SLC10A6) is a protein from Homo sapiens identified by UniProt accession Q3KNW5, 377 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q3KNW5; gene symbol SLC10A6.
- Organism: Homo sapiens.
- Length: 377 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): mean corpuscular hemoglobin, diastolic blood pressure and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sodium-dependent organic anion transporter |
|---|---|
| UniProt accession | Q3KNW5 |
| Gene | SLC10A6 |
| Organism | Homo sapiens |
| Length | 377 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin · score 0.33
- diastolic blood pressure · score 0.33
- body height · score 0.17
- sitting height measurement · score 0.15
- forced expiratory volume · score 0.09
- platelet count · score 0.08
- hypertriglyceridemia 2 · score 0.06
- cholesterol-ester transfer protein deficiency · score 0.06
- hypothyroidism · score 0.05
- lymphocyte percentage of leukocytes · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q3KNW5-F1 | alphafold | PREDICTED | 77.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q3KNW5.
Amino-acid sequence (377 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC10A6?
The strongest Open Targets associations for SLC10A6 are mean corpuscular hemoglobin, diastolic blood pressure, body height, sitting height measurement and forced expiratory volume.
How long is the SLC10A6 protein?
The Homo sapiens SLC10A6 protein (UniProt Q3KNW5) is 377 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q3KNW5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q3KNW5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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