Sodium-dependent organic anion transporter (SLC10A6)

About Sodium-dependent organic anion transporter

Sodium-dependent organic anion transporter (SLC10A6) is a protein from Homo sapiens identified by UniProt accession Q3KNW5, 377 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

Target properties

Protein name	Sodium-dependent organic anion transporter
UniProt accession	Q3KNW5
Gene	SLC10A6
Organism	Homo sapiens
Length	377 residues
Molecular weight	—
EC numbers	—
Target class	Transporter (inferred from UniProt keywords / EC)
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (54)

Diseases linked to this target (Open Targets).

mean corpuscular hemoglobin · score 0.33
diastolic blood pressure · score 0.33
body height · score 0.17
sitting height measurement · score 0.15
forced expiratory volume · score 0.09
platelet count · score 0.08
hypertriglyceridemia 2 · score 0.06
cholesterol-ester transfer protein deficiency · score 0.06
hypothyroidism · score 0.05
lymphocyte percentage of leukocytes · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3KNW5-F1	alphafold	PREDICTED	77.33	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q3KNW5.

Amino-acid sequence (377 residues)

MRANCSSSSA CPANSSEEEL PVGLEVHGNL ELVFTVVSTV MMGLLMFSLG CSVEIRKLWS HIRRPWGIAV GLLCQFGLMP FTAYLLAISF SLKPVQAIAV LIMGCCPGGT ISNIFTFWVD GDMDLSISMT TCSTVAALGM MPLCIYLYTW SWSLQQNLTI PYQNIGITLV CLTIPVAFGV YVNYRWPKQS KIILKIGAVV GGVLLLVVAV AGVVLAKGSW NSDITLLTIS FIFPLIGHVT GFLLALFTHQ SWQRCRTISL ETGAQNIQMC ITMLQLSFTA EHLVQMLSFP LAYGLFQLID GFLIVAAYQT YKRRLKNKHG KKNSGCTEVC HTRKSTSSRE TNAFLEVNEE GAITPGPPGP MDCHRALEPV GHITSCE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards