UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (UAP1L1)
Homo sapiens — UniProt Q3KQV9
Data last refreshed: (UniProt release unknown)
Key facts
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (UAP1L1) is a protein from Homo sapiens identified by UniProt accession Q3KQV9, 507 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q3KQV9; gene symbol UAP1L1.
- Organism: Homo sapiens.
- Length: 507 amino acids.
- Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, platelet count and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 |
|---|---|
| UniProt accession | Q3KQV9 |
| Gene | UAP1L1 |
| Organism | Homo sapiens |
| Length | 507 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.24
- platelet count · score 0.19
- monocyte count · score 0.11
- cerebrospinal fluid biomarker measurement · score 0.08
- leukocyte count · score 0.06
- neoplasm · score 0.06
- aspartate aminotransferase measurement · score 0.06
- esophageal squamous cell carcinoma · score 0.03
- glioblastoma · score 0.02
- basophil count · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q3KQV9-F1 | alphafold | PREDICTED | 93.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q3KQV9.
Amino-acid sequence (507 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UAP1L1?
The strongest Open Targets associations for UAP1L1 are high density lipoprotein cholesterol measurement, platelet count, monocyte count, cerebrospinal fluid biomarker measurement and leukocyte count.
How long is the UAP1L1 protein?
The Homo sapiens UAP1L1 protein (UniProt Q3KQV9) is 507 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q3KQV9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q3KQV9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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