UPF0538 protein C2orf76 (C2orf76)
Homo sapiens — UniProt Q3KRA6
Data last refreshed: (UniProt release unknown)
Key facts
UPF0538 protein C2orf76 (C2orf76) is a protein from Homo sapiens identified by UniProt accession Q3KRA6, 126 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q3KRA6; gene symbol C2orf76.
- Organism: Homo sapiens.
- Length: 126 amino acids.
- Top disease associations (Open Targets): metabolite measurement, protein measurement and breast cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UPF0538 protein C2orf76 |
|---|---|
| UniProt accession | Q3KRA6 |
| Gene | C2orf76 |
| Organism | Homo sapiens |
| Length | 126 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- metabolite measurement · score 0.22
- protein measurement · score 0.20
- breast cancer · score 0.01
- ulcerative colitis · score 0.00
- invasive breast ductal carcinoma · score 0.00
- meningococcal infection · score 0.00
- triple-negative breast cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q3KRA6-F1 | alphafold | PREDICTED | 92.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q3KRA6.
Amino-acid sequence (126 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C2orf76?
The strongest Open Targets associations for C2orf76 are metabolite measurement, protein measurement, breast cancer, ulcerative colitis and invasive breast ductal carcinoma.
How long is the C2orf76 protein?
The Homo sapiens C2orf76 protein (UniProt Q3KRA6) is 126 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q3KRA6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q3KRA6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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