Keratin-associated protein 25-1 (KRTAP25-1)
Homo sapiens — UniProt Q3LHN0
Data last refreshed: (UniProt release unknown)
Key facts
Keratin-associated protein 25-1 (KRTAP25-1) is a protein from Homo sapiens identified by UniProt accession Q3LHN0, 102 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.
- UniProt accession: Q3LHN0; gene symbol KRTAP25-1.
- Organism: Homo sapiens.
- Length: 102 amino acids.
- Top disease associations (Open Targets): clear cell renal carcinoma and gastric carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Keratin-associated protein 25-1 |
|---|---|
| UniProt accession | Q3LHN0 |
| Gene | KRTAP25-1 |
| Organism | Homo sapiens |
| Length | 102 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (2)
Diseases linked to this target (Open Targets).
- clear cell renal carcinoma · score 0.18
- gastric carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q3LHN0-F1 | alphafold | PREDICTED | 34.49 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q3LHN0.
Amino-acid sequence (102 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KRTAP25-1?
The strongest Open Targets associations for KRTAP25-1 are clear cell renal carcinoma and gastric carcinoma.
How long is the KRTAP25-1 protein?
The Homo sapiens KRTAP25-1 protein (UniProt Q3LHN0) is 102 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q3LHN0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q3LHN0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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