Keratin-associated protein 19-2 (KRTAP19-2)
Homo sapiens — UniProt Q3LHN2
Data last refreshed: (UniProt release unknown)
Key facts
Keratin-associated protein 19-2 (KRTAP19-2) is a protein from Homo sapiens identified by UniProt accession Q3LHN2, 52 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q3LHN2; gene symbol KRTAP19-2.
- Organism: Homo sapiens.
- Length: 52 amino acids.
- Top disease associations (Open Targets): clear cell renal carcinoma, glioblastoma multiforme and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Keratin-associated protein 19-2 |
|---|---|
| UniProt accession | Q3LHN2 |
| Gene | KRTAP19-2 |
| Organism | Homo sapiens |
| Length | 52 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- clear cell renal carcinoma · score 0.18
- glioblastoma multiforme · score 0.18
- breast adenocarcinoma · score 0.18
- low grade glioma · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q3LHN2-F1 | alphafold | PREDICTED | 43.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q3LHN2.
Amino-acid sequence (52 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KRTAP19-2?
The strongest Open Targets associations for KRTAP19-2 are clear cell renal carcinoma, glioblastoma multiforme, breast adenocarcinoma and low grade glioma.
How long is the KRTAP19-2 protein?
The Homo sapiens KRTAP19-2 protein (UniProt Q3LHN2) is 52 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q3LHN2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q3LHN2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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