Keratin-associated protein 22-1 (KRTAP22-1)

Homo sapiens — UniProt Q3MIV0

Gene: KRTAP22-1Homo sapiensSwissProt reviewed

About Keratin-associated protein 22-1

Keratin-associated protein 22-1 (KRTAP22-1) is a protein from Homo sapiens identified by UniProt accession Q3MIV0, 48 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein nameKeratin-associated protein 22-1
UniProt accessionQ3MIV0
GeneKRTAP22-1
OrganismHomo sapiens
Length48 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (4)

Diseases linked to this target (Open Targets).

  • head and neck squamous cell carcinoma · score 0.18
  • clear cell renal carcinoma · score 0.18
  • glioblastoma multiforme · score 0.18
  • smoking status measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q3MIV0-F1alphafoldPREDICTED40.76—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q3MIV0.

Amino-acid sequence (48 residues)

MSFDNNYHGG QGYAKGGLGC SYGCGLSGYG YACYCPWCYE RSWFSGCF

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Quick facts

UniProtQ3MIV0
GeneKRTAP22-1
OrganismHomo sapiens
Length48
Binders0
Diseases4
View on UniProt