Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (LRIT3)
Homo sapiens — UniProt Q3SXY7
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (LRIT3) is a protein from Homo sapiens identified by UniProt accession Q3SXY7, 679 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q3SXY7; gene symbol LRIT3.
- Organism: Homo sapiens.
- Length: 679 amino acids.
- Top disease associations (Open Targets): congenital stationary night blindness, Stargardt disease and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 |
|---|---|
| UniProt accession | Q3SXY7 |
| Gene | LRIT3 |
| Organism | Homo sapiens |
| Length | 679 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- congenital stationary night blindness · score 0.65
- Stargardt disease · score 0.43
- body height · score 0.39
- body weight · score 0.27
- lean body mass · score 0.25
- genetic disorder · score 0.19
- fat body mass · score 0.19
- whole body water mass · score 0.12
- base metabolic rate measurement · score 0.10
- platelet count · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q3SXY7-F1 | alphafold | PREDICTED | 69.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q3SXY7.
Amino-acid sequence (679 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRIT3?
The strongest Open Targets associations for LRIT3 are congenital stationary night blindness, Stargardt disease, body height, body weight and lean body mass.
How long is the LRIT3 protein?
The Homo sapiens LRIT3 protein (UniProt Q3SXY7) is 679 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q3SXY7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q3SXY7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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