ADP-ribosylation factor-like protein 13B (ARL13B)
Homo sapiens — UniProt Q3SXY8
Data last refreshed: (UniProt release unknown)
Key facts
ADP-ribosylation factor-like protein 13B (ARL13B) is a protein from Homo sapiens identified by UniProt accession Q3SXY8, 428 residues long. MolForge cross-references it against 0 known binders and 127 disease associations.
- UniProt accession: Q3SXY8; gene symbol ARL13B.
- Organism: Homo sapiens.
- Length: 428 amino acids.
- Top disease associations (Open Targets): Joubert syndrome, genetic disorder and Joubert syndrome and related disorders.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ADP-ribosylation factor-like protein 13B |
|---|---|
| UniProt accession | Q3SXY8 |
| Gene | ARL13B |
| Organism | Homo sapiens |
| Length | 428 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (127)
Diseases linked to this target (Open Targets).
- Joubert syndrome · score 0.78
- genetic disorder · score 0.41
- Joubert syndrome and related disorders · score 0.41
- Intellectual disability · score 0.37
- blood protein measurement · score 0.20
- body mass index · score 0.17
- body fat percentage · score 0.16
- lean body mass · score 0.16
- self reported educational attainment · score 0.15
- fat body mass · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q3SXY8-F1 | alphafold | PREDICTED | 72.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q3SXY8.
Amino-acid sequence (428 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARL13B?
The strongest Open Targets associations for ARL13B are Joubert syndrome, genetic disorder, Joubert syndrome and related disorders, Intellectual disability and blood protein measurement.
How long is the ARL13B protein?
The Homo sapiens ARL13B protein (UniProt Q3SXY8) is 428 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q3SXY8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q3SXY8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.