Zinc finger protein 718 (ZNF718)
Homo sapiens — UniProt Q3SXZ3
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 718 (ZNF718) is a protein from Homo sapiens identified by UniProt accession Q3SXZ3, 478 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q3SXZ3; gene symbol ZNF718.
- Organism: Homo sapiens.
- Length: 478 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cerebrospinal fluid biomarker measurement and interleukin 8 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 718 |
|---|---|
| UniProt accession | Q3SXZ3 |
| Gene | ZNF718 |
| Organism | Homo sapiens |
| Length | 478 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.16
- cerebrospinal fluid biomarker measurement · score 0.13
- interleukin 8 measurement · score 0.13
- periodontitis · score 0.02
- type 2 diabetes mellitus · score 0.01
- head and neck squamous cell carcinoma · score 0.00
- hepatocellular carcinoma · score 0.00
- diabetes mellitus · score 0.00
- cystic fibrosis · score 0.00
- Herpes simplex infection · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q3SXZ3-F1 | alphafold | PREDICTED | 70.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q3SXZ3.
Amino-acid sequence (478 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF718?
The strongest Open Targets associations for ZNF718 are neurodegenerative disease, cerebrospinal fluid biomarker measurement, interleukin 8 measurement, periodontitis and type 2 diabetes mellitus.
How long is the ZNF718 protein?
The Homo sapiens ZNF718 protein (UniProt Q3SXZ3) is 478 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q3SXZ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q3SXZ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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