Rab-like protein 6 (RABL6)
Homo sapiens — UniProt Q3YEC7
Data last refreshed: (UniProt release unknown)
Key facts
Rab-like protein 6 (RABL6) is a protein from Homo sapiens identified by UniProt accession Q3YEC7, 729 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q3YEC7; gene symbol RABL6.
- Organism: Homo sapiens.
- Length: 729 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Meniere disease and esophageal squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Rab-like protein 6 |
|---|---|
| UniProt accession | Q3YEC7 |
| Gene | RABL6 |
| Organism | Homo sapiens |
| Length | 729 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- Meniere disease · score 0.15
- esophageal squamous cell carcinoma · score 0.08
- breast cancer · score 0.07
- neoplasm · score 0.05
- hepatocellular carcinoma · score 0.04
- non-small cell lung carcinoma · score 0.04
- cancer · score 0.04
- melorheostosis · score 0.03
- 12q14 microdeletion syndrome · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q3YEC7-F1 | alphafold | PREDICTED | 59.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q3YEC7.
Amino-acid sequence (729 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RABL6?
The strongest Open Targets associations for RABL6 are neurodegenerative disease, Meniere disease, esophageal squamous cell carcinoma, breast cancer and neoplasm.
How long is the RABL6 protein?
The Homo sapiens RABL6 protein (UniProt Q3YEC7) is 729 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q3YEC7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q3YEC7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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