Speedy protein E2 (SPDYE2)
Homo sapiens — UniProt Q495Y8
Data last refreshed: (UniProt release unknown)
Key facts
Speedy protein E2 (SPDYE2) is a protein from Homo sapiens identified by UniProt accession Q495Y8, 402 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.
- UniProt accession: Q495Y8; gene symbol SPDYE2.
- Organism: Homo sapiens.
- Length: 402 amino acids.
- Top disease associations (Open Targets): neuronal ceroid lipofuscinosis 1 and diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Speedy protein E2 |
|---|---|
| UniProt accession | Q495Y8 |
| Gene | SPDYE2 |
| Organism | Homo sapiens |
| Length | 402 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (2)
Diseases linked to this target (Open Targets).
- neuronal ceroid lipofuscinosis 1 · score 0.03
- diabetes mellitus · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q495Y8-F1 | alphafold | PREDICTED | 60.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q495Y8.
Amino-acid sequence (402 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPDYE2?
The strongest Open Targets associations for SPDYE2 are neuronal ceroid lipofuscinosis 1 and diabetes mellitus.
How long is the SPDYE2 protein?
The Homo sapiens SPDYE2 protein (UniProt Q495Y8) is 402 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q495Y8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q495Y8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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