Schlafen-like protein 1 (SLFNL1)
Homo sapiens — UniProt Q499Z3
Data last refreshed: (UniProt release unknown)
Key facts
Schlafen-like protein 1 (SLFNL1) is a protein from Homo sapiens identified by UniProt accession Q499Z3, 407 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q499Z3; gene symbol SLFNL1.
- Organism: Homo sapiens.
- Length: 407 amino acids.
- Top disease associations (Open Targets): diastolic blood pressure, heel bone mineral density and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Schlafen-like protein 1 |
|---|---|
| UniProt accession | Q499Z3 |
| Gene | SLFNL1 |
| Organism | Homo sapiens |
| Length | 407 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.36
- heel bone mineral density · score 0.35
- body height · score 0.20
- lean body mass · score 0.20
- body weight · score 0.18
- forced expiratory volume · score 0.18
- vital capacity · score 0.17
- platelet crit · score 0.17
- mathematical ability · score 0.15
- fat body mass · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q499Z3-F1 | alphafold | PREDICTED | 71.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q499Z3.
Amino-acid sequence (407 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLFNL1?
The strongest Open Targets associations for SLFNL1 are diastolic blood pressure, heel bone mineral density, body height, lean body mass and body weight.
How long is the SLFNL1 protein?
The Homo sapiens SLFNL1 protein (UniProt Q499Z3) is 407 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q499Z3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q499Z3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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