Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 (MINDY4)
Homo sapiens — UniProt Q4G0A6
Data last refreshed: (UniProt release unknown)
Key facts
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 (MINDY4) is a protein from Homo sapiens identified by UniProt accession Q4G0A6, 757 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q4G0A6; gene symbol MINDY4.
- Organism: Homo sapiens.
- Length: 757 amino acids.
- Top disease associations (Open Targets): urolithiasis, breast milk measurement and nephrolithiasis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 |
|---|---|
| UniProt accession | Q4G0A6 |
| Gene | MINDY4 |
| Organism | Homo sapiens |
| Length | 757 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- urolithiasis · score 0.31
- breast milk measurement · score 0.30
- nephrolithiasis · score 0.21
- urate measurement · score 0.20
- systolic blood pressure · score 0.16
- BMI-adjusted waist-hip ratio · score 0.14
- waist-hip ratio · score 0.10
- cystatin C measurement · score 0.10
- uric acid measurement · score 0.09
- neoplasm · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q4G0A6-F1 | alphafold | PREDICTED | 68.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4G0A6.
Amino-acid sequence (757 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MINDY4?
The strongest Open Targets associations for MINDY4 are urolithiasis, breast milk measurement, nephrolithiasis, urate measurement and systolic blood pressure.
How long is the MINDY4 protein?
The Homo sapiens MINDY4 protein (UniProt Q4G0A6) is 757 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q4G0A6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q4G0A6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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