About La-related protein 7
La-related protein 7 (LARP7) is a protein
from Homo sapiens identified by UniProt accession
Q4G0J3, 582 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (69)
Diseases linked to this target (Open Targets).
- microcephalic primordial dwarfism, Alazami type · score 0.78
- isolated growth hormone deficiency type IA · score 0.37
- Alazami-Yuan syndrome · score 0.37
- Epileptic encephalopathy · score 0.34
- body height · score 0.29
- Abnormal brain morphology · score 0.27
- Intellectual disability · score 0.26
- appendicular lean mass · score 0.26
- genetic disorder · score 0.19
- alcohol consumption measurement · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q4G0J3.
Amino-acid sequence (582 residues)
METESGNQEK VMEEESTEKK KEVEKKKRSR VKQVLADIAK QVDFWFGDAN LHKDRFLREQ IEKSRDGYVD ISLLVSFNKM KKLTTDGKLI ARALRSSAVV ELDLEGTRIR RKKPLGERPK DEDERTVYVE LLPKNVNHSW IERVFGKCGN VVYISIPHYK STGDPKGFAF VEFETKEQAA KAIEFLNNPP EEAPRKPGIF PKTVKNKPIP ALRVVEEKKK KKKKKGRMKK EDNIQAKEEN MDTSNTSISK MKRSRPTSEG SDIESTEPQK QCSKKKKKRD RVEASSLPEV RTGKRKRSSS EDAESLAPRS KVKKIIQKDI IKEASEASKE NRDIEISTEE EKDTGDLKDS SLLKTKRKHK KKHKERHKMG EEVIPLRVLS KSEWMDLKKE YLALQKASMA SLKKTISQIK SESEMETDSG VPQNTGMKNE KTANREECRT QEKVNATGPQ FVSGVIVKII STEPLPGRKQ VRDTLAAISE VLYVDLLEGD TECHARFKTP EDAQAVINAY TEINKKHCWK LEILSGDHEQ RYWQKILVDR QAKLNQPREK KRGTEKLITK AEKIRLAKTQ QASKHIRFSE YD
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