Inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase (GGTA1)
Homo sapiens — UniProt Q4G0N0
Data last refreshed: (UniProt release unknown)
Key facts
Inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase (GGTA1) is a protein from Homo sapiens identified by UniProt accession Q4G0N0, 100 residues long. MolForge cross-references it against 0 known binders and 117 disease associations.
- UniProt accession: Q4G0N0; gene symbol GGTA1.
- Organism: Homo sapiens.
- Length: 100 amino acids.
- Top disease associations (Open Targets): body height, appendicular lean mass and early-onset non-syndromic cataract.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase |
|---|---|
| UniProt accession | Q4G0N0 |
| Gene | GGTA1 |
| Organism | Homo sapiens |
| Length | 100 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (117)
Diseases linked to this target (Open Targets).
- body height · score 0.36
- appendicular lean mass · score 0.17
- early-onset non-syndromic cataract · score 0.10
- Posterior polar cataract · score 0.09
- Total congenital cataract · score 0.09
- Cataract-microcornea syndrome · score 0.09
- cataract · score 0.09
- Cataract with Y-shaped suture opacities · score 0.08
- Anterior polar cataract · score 0.08
- hereditary hyperferritinemia with congenital cataracts · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q4G0N0-F1 | alphafold | PREDICTED | 63.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4G0N0.
Amino-acid sequence (100 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GGTA1?
The strongest Open Targets associations for GGTA1 are body height, appendicular lean mass, early-onset non-syndromic cataract, Posterior polar cataract and Total congenital cataract.
How long is the GGTA1 protein?
The Homo sapiens GGTA1 protein (UniProt Q4G0N0) is 100 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q4G0N0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q4G0N0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.