Cytochrome P450 27C1 (CYP27C1)
Homo sapiens — UniProt Q4G0S4
Data last refreshed: (UniProt release unknown)
Key facts
Cytochrome P450 27C1 (CYP27C1) is a protein from Homo sapiens identified by UniProt accession Q4G0S4, 542 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q4G0S4; gene symbol CYP27C1.
- Organism: Homo sapiens.
- Length: 542 amino acids.
- Top disease associations (Open Targets): protein C measurement, self reported educational attainment and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytochrome P450 27C1 |
|---|---|
| UniProt accession | Q4G0S4 |
| Gene | CYP27C1 |
| Organism | Homo sapiens |
| Length | 542 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- protein C measurement · score 0.38
- self reported educational attainment · score 0.15
- body height · score 0.09
- Alzheimer disease · score 0.08
- family history of Alzheimer’s disease · score 0.07
- visual perception measurement · score 0.06
- Dementia · score 0.05
- high density lipoprotein cholesterol measurement · score 0.04
- blood protein measurement · score 0.04
- Lewy body dementia · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q4G0S4-F1 | alphafold | PREDICTED | 85.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4G0S4.
Amino-acid sequence (542 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CYP27C1?
The strongest Open Targets associations for CYP27C1 are protein C measurement, self reported educational attainment, body height, Alzheimer disease and family history of Alzheimer’s disease.
How long is the CYP27C1 protein?
The Homo sapiens CYP27C1 protein (UniProt Q4G0S4) is 542 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q4G0S4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q4G0S4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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