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Coiled-coil domain-containing protein 152 (CCDC152)

Homo sapiens — UniProt Q4G0S7

Gene: CCDC152Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Coiled-coil domain-containing protein 152 (CCDC152) is a protein from Homo sapiens identified by UniProt accession Q4G0S7, 254 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

  • UniProt accession: Q4G0S7; gene symbol CCDC152.
  • Organism: Homo sapiens.
  • Length: 254 amino acids.
  • Top disease associations (Open Targets): lean body mass, body height and body weight.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCoiled-coil domain-containing protein 152
UniProt accessionQ4G0S7
GeneCCDC152
OrganismHomo sapiens
Length254 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (32)

Diseases linked to this target (Open Targets).

  • lean body mass · score 0.41
  • body height · score 0.34
  • body weight · score 0.30
  • fat body mass · score 0.28
  • appendicular lean mass · score 0.24
  • blood protein measurement · score 0.24
  • sitting height measurement · score 0.23
  • whole body water mass · score 0.22
  • BMI-adjusted hip circumference · score 0.21
  • forced expiratory volume · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q4G0S7-F1alphafoldPREDICTED87.03—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4G0S7.

Amino-acid sequence (254 residues)

MDQSSEGCMK KISSVNLDKL INDFSQIEKK MVETNGKNNI LDIQLEKSNC LLKVMQAKEV SIKEECATLH NIIKGLQQTI EYQQNLKGEN EQLKISADLI KEKLKSHEQE YKNNIAKLVS EMKIKEEGYK KEISKLYQDM QRKVELNEEK HKELIEKKEM EISELNAKLR SQEKEKQNEI IKLQLEFDAK LARVQTKSKS YQDSTVLPQS IYRRKLQHFQ EEKNKEIAIL RNTIRDLEQR LSVGKDSHLK RRRF

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CCDC152?

The strongest Open Targets associations for CCDC152 are lean body mass, body height, body weight, fat body mass and appendicular lean mass.

How long is the CCDC152 protein?

The Homo sapiens CCDC152 protein (UniProt Q4G0S7) is 254 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ4G0S7
GeneCCDC152
OrganismHomo sapiens
Length254
Binders0
Diseases32
View on UniProt