Scavenger receptor cysteine-rich domain-containing protein SCART1 (SCART1)
Homo sapiens — UniProt Q4G0T1
Data last refreshed: (UniProt release unknown)
Key facts
Scavenger receptor cysteine-rich domain-containing protein SCART1 (SCART1) is a protein from Homo sapiens identified by UniProt accession Q4G0T1, 1027 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q4G0T1; gene symbol SCART1.
- Organism: Homo sapiens.
- Length: 1027 amino acids.
- Top disease associations (Open Targets): Primary amenorrhea, primary ovarian insufficiency and DNA methylation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Scavenger receptor cysteine-rich domain-containing protein SCART1 |
|---|---|
| UniProt accession | Q4G0T1 |
| Gene | SCART1 |
| Organism | Homo sapiens |
| Length | 1027 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- Primary amenorrhea · score 0.32
- primary ovarian insufficiency · score 0.27
- DNA methylation · score 0.08
- Sepsis · score 0.03
- Pneumonia · score 0.01
- dermatitis · score 0.01
- Inflammatory abnormality of the skin · score 0.01
- ulcerative colitis · score 0.01
- inflammatory bowel disease · score 0.01
- Crohn's disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q4G0T1-F1 | alphafold | PREDICTED | 69.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4G0T1.
Amino-acid sequence (1027 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SCART1?
The strongest Open Targets associations for SCART1 are Primary amenorrhea, primary ovarian insufficiency, DNA methylation, Sepsis and Pneumonia.
How long is the SCART1 protein?
The Homo sapiens SCART1 protein (UniProt Q4G0T1) is 1027 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q4G0T1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q4G0T1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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