GLIPR1-like protein 2 (GLIPR1L2)
Homo sapiens — UniProt Q4G1C9
Data last refreshed: (UniProt release unknown)
Key facts
GLIPR1-like protein 2 (GLIPR1L2) is a protein from Homo sapiens identified by UniProt accession Q4G1C9, 344 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q4G1C9; gene symbol GLIPR1L2.
- Organism: Homo sapiens.
- Length: 344 amino acids.
- Top disease associations (Open Targets): bone density, urate measurement and cup-to-disc ratio measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | GLIPR1-like protein 2 |
|---|---|
| UniProt accession | Q4G1C9 |
| Gene | GLIPR1L2 |
| Organism | Homo sapiens |
| Length | 344 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- bone density · score 0.19
- urate measurement · score 0.19
- cup-to-disc ratio measurement · score 0.05
- intrathoracic organ injury · score 0.04
- age at menopause · score 0.03
- polycystic ovary syndrome · score 0.02
- multiple myeloma · score 0.02
- lung adenocarcinoma · score 0.01
- cancer · score 0.01
- Miyoshi myopathy · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q4G1C9-F1 | alphafold | PREDICTED | 85.31 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4G1C9.
Amino-acid sequence (344 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GLIPR1L2?
The strongest Open Targets associations for GLIPR1L2 are bone density, urate measurement, cup-to-disc ratio measurement, intrathoracic organ injury and age at menopause.
How long is the GLIPR1L2 protein?
The Homo sapiens GLIPR1L2 protein (UniProt Q4G1C9) is 344 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q4G1C9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q4G1C9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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