Anoctamin-6 (ANO6)
Homo sapiens — UniProt Q4KMQ2
Data last refreshed: (UniProt release unknown)
Key facts
Anoctamin-6 (ANO6) is a protein from Homo sapiens identified by UniProt accession Q4KMQ2, 910 residues long. MolForge cross-references it against 0 known binders and 308 disease associations.
- UniProt accession: Q4KMQ2; gene symbol ANO6.
- Organism: Homo sapiens.
- Length: 910 amino acids.
- Top disease associations (Open Targets): Scott syndrome, COVID-19 and ulcerative colitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Anoctamin-6 |
|---|---|
| UniProt accession | Q4KMQ2 |
| Gene | ANO6 |
| Organism | Homo sapiens |
| Length | 910 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (308)
Diseases linked to this target (Open Targets).
- Scott syndrome · score 0.72
- COVID-19 · score 0.37
- ulcerative colitis · score 0.27
- ankylosing spondylitis · score 0.22
- genetic disorder · score 0.19
- type 2 diabetes mellitus · score 0.17
- breast adenocarcinoma · score 0.16
- arterial stiffness measurement · score 0.13
- head and neck squamous cell carcinoma · score 0.12
- Von Willebrand disease · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q4KMQ2-F1 | alphafold | PREDICTED | 81.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4KMQ2.
Amino-acid sequence (910 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANO6?
The strongest Open Targets associations for ANO6 are Scott syndrome, COVID-19, ulcerative colitis, ankylosing spondylitis and genetic disorder.
How long is the ANO6 protein?
The Homo sapiens ANO6 protein (UniProt Q4KMQ2) is 910 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q4KMQ2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q4KMQ2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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