IQ domain-containing protein C (IQCC)

About IQ domain-containing protein C

IQ domain-containing protein C (IQCC) is a protein from Homo sapiens identified by UniProt accession Q4KMZ1, 466 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein name	IQ domain-containing protein C
UniProt accession	Q4KMZ1
Gene	IQCC
Organism	Homo sapiens
Length	466 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (2)

Diseases linked to this target (Open Targets).

juvenile dermatomyositis · score 0.01
spina bifida · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q4KMZ1-F1	alphafold	PREDICTED	51.35	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4KMZ1.

Amino-acid sequence (466 residues)

MEPELLVRKV SALQACVRGF LVRRQFQSLR AEYEAIVREV EGDLGTLQWT EGRIPRPRFL PEKAKSHQTW KAGDRVANPE QGLWNHFPCE ESEGEATWEE MVLKKSGESS ANQGSLCRDH SSWLQMKQNR KPSQEKTRDT TRMENPEATD QRLPHSQPQL QELQYHRSHL AMELLWLQQA INSRKEYLLL KQTLRSPEAG PIREEPRVFL EHGEQACERD QSQPSAPLED QSYRDRTTGE LEQEDDSCHR VKSPHRSPGS LATTQKNIAG AKCREPCYSK SGPPSSIPSN SQALGDRLTK GPDDGRQTFG GTCLLQMKIL EDQTPRGLKP RNHCPRKSRT QLSALYEDSN IKEMSPRKLD HKEPDCRTVR TQELGLSEDH IIWDGTLGGP EHSVLDLWRT KPPKGQAPTD RSSRDGTSNE PSHEGQKKQR TIPWRSKSPE ILSSTKAGCT GEEQWRGRPW KTEPPG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards