Large ribosomal subunit protein mL51 (MRPL51)
Homo sapiens — UniProt Q4U2R6
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein mL51 (MRPL51) is a protein from Homo sapiens identified by UniProt accession Q4U2R6, 128 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q4U2R6; gene symbol MRPL51.
- Organism: Homo sapiens.
- Length: 128 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, blood protein measurement and Back pain.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein mL51 |
|---|---|
| UniProt accession | Q4U2R6 |
| Gene | MRPL51 |
| Organism | Homo sapiens |
| Length | 128 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- blood protein measurement · score 0.11
- Back pain · score 0.09
- lung adenocarcinoma · score 0.08
- monocyte count · score 0.06
- dicarboxylic aminoaciduria · score 0.05
- Idiopathic hypercalciuria · score 0.05
- neoplasm · score 0.04
- MODY · score 0.04
- ketoacidosis due to monocarboxylate transporter-1 deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q4U2R6-F1 | alphafold | PREDICTED | 85.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4U2R6.
Amino-acid sequence (128 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPL51?
The strongest Open Targets associations for MRPL51 are neurodegenerative disease, blood protein measurement, Back pain, lung adenocarcinoma and monocyte count.
How long is the MRPL51 protein?
The Homo sapiens MRPL51 protein (UniProt Q4U2R6) is 128 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q4U2R6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q4U2R6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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