Large ribosomal subunit protein mL51 (MRPL51)

About Large ribosomal subunit protein mL51

Large ribosomal subunit protein mL51 (MRPL51) is a protein from Homo sapiens identified by UniProt accession Q4U2R6, 128 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

Target properties

Protein name	Large ribosomal subunit protein mL51
UniProt accession	Q4U2R6
Gene	MRPL51
Organism	Homo sapiens
Length	128 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (37)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
blood protein measurement · score 0.11
Back pain · score 0.09
lung adenocarcinoma · score 0.08
monocyte count · score 0.06
dicarboxylic aminoaciduria · score 0.05
Idiopathic hypercalciuria · score 0.05
neoplasm · score 0.04
MODY · score 0.04
ketoacidosis due to monocarboxylate transporter-1 deficiency · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q4U2R6-F1	alphafold	PREDICTED	85.86	—

Amino-acid sequence (128 residues)

MAGNLLSGAG RRLWDWVPLA CRSFSLGVPR LIGIRLTLPP PKVVDRWNEK RAMFGVYDNI GILGNFEKHP KELIRGPIWL RGWKGNELQR CIRKRKMVGS RMFADDLHNL NKRIRYLYKH FNRHGKFR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards