Probable cation-transporting ATPase 13A4 (ATP13A4)
Homo sapiens — UniProt Q4VNC1
Data last refreshed: (UniProt release unknown)
Key facts
Probable cation-transporting ATPase 13A4 (ATP13A4) is a protein from Homo sapiens identified by UniProt accession Q4VNC1, 1196 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.
- UniProt accession: Q4VNC1; gene symbol ATP13A4.
- Organism: Homo sapiens.
- Length: 1196 amino acids.
- Top disease associations (Open Targets): dentures, dental caries and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable cation-transporting ATPase 13A4 |
|---|---|
| UniProt accession | Q4VNC1 |
| Gene | ATP13A4 |
| Organism | Homo sapiens |
| Length | 1196 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (76)
Diseases linked to this target (Open Targets).
- dentures · score 0.29
- dental caries · score 0.24
- mathematical ability · score 0.22
- depressive symptom measurement · score 0.22
- age at menopause · score 0.21
- neuroimaging measurement · score 0.19
- brain volume measurement · score 0.19
- self reported educational attainment · score 0.17
- cortical surface area measurement · score 0.16
- FEV/FVC ratio · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q4VNC1-F1 | alphafold | PREDICTED | 80.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4VNC1.
Amino-acid sequence (1196 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATP13A4?
The strongest Open Targets associations for ATP13A4 are dentures, dental caries, mathematical ability, depressive symptom measurement and age at menopause.
How long is the ATP13A4 protein?
The Homo sapiens ATP13A4 protein (UniProt Q4VNC1) is 1196 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q4VNC1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q4VNC1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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