Synaptotagmin-like protein 3 (SYTL3)
Homo sapiens — UniProt Q4VX76
Data last refreshed: (UniProt release unknown)
Key facts
Synaptotagmin-like protein 3 (SYTL3) is a protein from Homo sapiens identified by UniProt accession Q4VX76, 610 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q4VX76; gene symbol SYTL3.
- Organism: Homo sapiens.
- Length: 610 amino acids.
- Top disease associations (Open Targets): lipoprotein A measurement, hair color and alkaline phosphatase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptotagmin-like protein 3 |
|---|---|
| UniProt accession | Q4VX76 |
| Gene | SYTL3 |
| Organism | Homo sapiens |
| Length | 610 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- lipoprotein A measurement · score 0.37
- hair color · score 0.32
- alkaline phosphatase measurement · score 0.15
- plasma fibronectin deficiency · score 0.07
- isolated asymptomatic elevation of creatine phosphokinase · score 0.06
- hair colour measurement · score 0.06
- FEV/FVC ratio · score 0.05
- PHF-tau measurement · score 0.05
- coronary artery disease · score 0.04
- Hereditary persistence of alpha-fetoprotein · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q4VX76-F1 | alphafold | PREDICTED | 71.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4VX76.
Amino-acid sequence (610 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYTL3?
The strongest Open Targets associations for SYTL3 are lipoprotein A measurement, hair color, alkaline phosphatase measurement, plasma fibronectin deficiency and isolated asymptomatic elevation of creatine phosphokinase.
How long is the SYTL3 protein?
The Homo sapiens SYTL3 protein (UniProt Q4VX76) is 610 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q4VX76 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q4VX76 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.