Dopamine receptor-interacting protein 1 (DORIP1)
Homo sapiens — UniProt Q4W4Y0
Data last refreshed: (UniProt release unknown)
Key facts
Dopamine receptor-interacting protein 1 (DORIP1) is a protein from Homo sapiens identified by UniProt accession Q4W4Y0, 310 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q4W4Y0; gene symbol DORIP1.
- Organism: Homo sapiens.
- Length: 310 amino acids.
- Top disease associations (Open Targets): nicotine dependence symptom count, self reported educational attainment and pyelonephritis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dopamine receptor-interacting protein 1 |
|---|---|
| UniProt accession | Q4W4Y0 |
| Gene | DORIP1 |
| Organism | Homo sapiens |
| Length | 310 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- nicotine dependence symptom count · score 0.33
- self reported educational attainment · score 0.24
- pyelonephritis · score 0.21
- sphingomyelin measurement · score 0.04
- body height · score 0.02
- Acute hepatic failure · score 0.02
- metabolite measurement · score 0.02
- Abnormal sperm morphology · score 0.01
- schizophrenia · score 0.01
- psoriasis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q4W4Y0-F1 | alphafold | PREDICTED | 82.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q4W4Y0.
Amino-acid sequence (310 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DORIP1?
The strongest Open Targets associations for DORIP1 are nicotine dependence symptom count, self reported educational attainment, pyelonephritis, sphingomyelin measurement and body height.
How long is the DORIP1 protein?
The Homo sapiens DORIP1 protein (UniProt Q4W4Y0) is 310 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q4W4Y0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q4W4Y0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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